Please note that the corresponding author must submit an institutional email for the paper to be considered for peer review. If this is not available, then please motivate this in the cover letter for editorial evaluation. To submit a manuscript, fill in the following form and click the Submit button. The manuscript should be uploaded as one file with tables and figures included. MANUSCRIPT THAT DO NOT ADHERE TO THE FOLLOWING INSTRUCTIONS WILL BE RETURNED TO THE CORRESPONDING AUTHOR FOR TECHNICAL REVISION BEFORE UNDERGOING PEER REVIEW: http://www.iospress.nl/journal/restorative-neurology-and-neuroscience/. There is a publication fee for all articles accepted for publication. Authors pay EUR 750/US$ 750 for each article that is accepted for publication. Enter the corresponding author's information below. The cover letter MUST include the names and email addresses of 5-7 potential reviewers knowledgeable in the area of the study and potential reviewer conflicts. Not including reviewer suggestions will delay the handling of your submission. RESUBMISSION: A resubmission should always be a Word file and the article reference number should be mentioned in the cover letter. The point-by-point response should be included as part of the cover letter.